Poona Diagnostic Centre

The Liver Function Test (LFT) is a blood test used to assess the health and functionality of the liver by measuring the levels of various proteins, enzymes, and bilirubin. This test provides vital information about liver function, helping to diagnose liver diseases, monitor existing liver conditions, and assess the effects of medications or treatments.

1. Alanine Aminotransferase (ALT):

   • An enzyme found primarily in the liver. Elevated ALT levels often indicate liver damage, such as from hepatitis, fatty liver disease, or liver injury.
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2. Aspartate Aminotransferase (AST):

   • An enzyme present in the liver, heart, muscles, and kidneys. High AST levels can indicate liver damage, though it is less specific than ALT.
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3. Alkaline Phosphatase (ALP):

   • An enzyme found in the liver, bones, kidneys, and bile ducts. Elevated ALP levels may suggest liver disease, bile duct obstruction, or bone disorders.
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4. Bilirubin:

   • A waste product produced by the breakdown of red blood cells. High bilirubin levels may cause jaundice (yellowing of the skin and eyes) and indicate liver dysfunction, bile duct problems, or hemolysis.
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5. Albumin:

   • A protein produced by the liver. Low albumin levels can indicate liver disease, kidney problems, or malnutrition.
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6. Total Protein:

   • Measures the total amount of protein in the blood, including albumin and globulins. Low levels can suggest liver disease or other conditions that affect protein production.
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7. Gamma-Glutamyl Transferase (GGT):

   • An enzyme that can indicate liver disease, bile duct problems, or alcohol abuse when elevated.

• Diagnosing Liver Diseases: Helps detect liver conditions such as hepatitis, cirrhosis, liver tumors, or fatty liver disease.
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• Monitoring Chronic Conditions: Used to monitor the progress of chronic liver diseases and assess the effects of medications or treatments.
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• Assessing Bile Duct Function: Evaluates issues such as gallstones or blockages in bile ducts.
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• General Health Screening: Part of routine check-ups, especially for those at risk of liver problems due to alcohol consumption, viral infections, or metabolic diseases.

LFTs are recommended for individuals with:

• Symptoms of liver disease (e.g., jaundice, abdominal pain, fatigue).
• Risk factors such as excessive alcohol use, obesity, diabetes, or a history of hepatitis.
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• Monitoring liver health during treatments that may affect liver function, such as certain medications.

Early identification of liver problems allows for timely intervention, lifestyle changes, and medical treatment to prevent further liver damage and improve overall health. Regular liver function testing ensures that liver conditions are managed effectively, reducing the risk of serious complications like liver failure or cirrhosis.